Where is St. Marys

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Directions to St. Marys, PA

The community of St. Marys is located in northwestern Pennsylvania about halfway between Pittsburgh, Pennsylvania and Buffalo, New York. St. Marys is 30 miles north on State Route 255 from interstate 80 (Penfield Exit), and about 50 miles south from the New York State border on U.S. Route 219 and Route 255.

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